| ncRNA name | hsa-miR-186 |
| ncRNA Category | miRNA |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | retinal tissue samples; human RPE cell line ARPE-19; human RB cell line Y79, WERI-RB1 and SORB50 |
| Methods | qRT-PCR, Western blot, luciferase reporter assay, CCK-8 assay, cell cycle assay, transwell assay |
| Expression pattern | down-regulated |
| Functional description | miR-186 is downregulated in RB and inversely correlates with DIXDC1.It targets DIXDC1 3’-UTR and regulates its expression.Overexpression of miR-186 inhibits the proliferation and invasion of RB Cells. |
| PubMed ID | 29264763 |
| Year | 2018 |
| Title | Suppression of Disheveled-Axin Domain Containing 1 (DIXDC1) by MicroRNA-186 Inhibits the Proliferation and Invasion of Retinoblastoma Cells. |
| Drug-related ncRNA | NO |
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